Neonatal thrombocytopenia: Causes, Symptoms & Treatments
Causes The definition of neonatal thrombocytopenia is defined as 150,000 / μL or less, and 1 to 2% may occur in normal children, but most of them have few symptoms and severely decrease to less than 50,000 in some cases. Most causes are classified according to the timing of platelet reduction. Placental dysfunction (preeclampsia, intrauterine growth retardation, etc.) and perinatal history of early onset occurring within 72 hours of birth. It may be considered a perinatal infection (eg E. coli, GBS, Haemophilus infuenzae), DIC, homologous immunity, autoimmune, congenital infection, thrombosis, metabolic disease, hereditary congenital disease and Kasabach-Merritt syndrome. Late onset after 72 hours of birth may be caused by delayed onset sepsis, neonatal necrotizing enteritis, congenital infection, metabolic disease, autoimmune, hereditary congenital disease. Immune thrombocytopenia is largely autoimmune and allogeneic. Autoimmunity is the case when an anti-platelet antibody is ...