Acute lymphoblastic leukemia(ALL): Symptoms, Diagnosis, Prognosis factors & Treatments
Symptoms Leukemia is the most common cancer among childhood cancers. Among them, Acute lymphoblastic leukemia (ALL) is the most common cause, and ALL is the most common cancer among childhood cancers. Clinical symptoms of ALL are very nonspecific. Fever, hemorrhagic tendency, bone pain, enlargement of the lymph nodes, and splenomegaly. If these nonspecific symptoms persist without resolution, ALL should always be suspected in children. Diagnosis ALL can be classified as morphological, CD marker, or cytogenetic. The morphological classification follows the FAB classification and is classified into L1, L2, and L3 according to the shape through the Bone marrow biopsy. CD markers can be used to determine whether this ALL is a T cell lineage or B cell lineage. Most of ALL is B cell lineage, and the T cell lineage has a poor prognosis. The cytogenetic classification is based on chromosomal studies to classify ALL based on chromosomal anomalies or presence or absence of genes. Philadelphi...