MedClips

Stevens-Johnson syndrome is a serious skin disorder characterized by extensive necrosis and deprivation of the epidermis, usually caused by drugs. Stevens-Johnson syndrome is a relatively minor disease, which refers to the deprivation of less than 10% of the total body surface area. When more than 30% of the total body surface area is deprived, it is called a toxic epidermal necrosis. Causes The most common cause of Stevens-Johnson syndrome is medication. In general, allopurinol, aromatic anticonvulsant, antibacterial sulfonamide, lamotrigine, Nevirapine, and NSAIDs are thought to be the causative drugs. Especially in children, drugs such as antibacterial sulfonamide, phenobarbital, carbamazepine, lamotrigine and acetaminophen have been reported. Stevens-Johnson syndrome is common in infections of mycoplasma pneumonia and cytomegalovirus infection. Vaccination, systemic disease, contrast agent, chemical exposure, herbal medicines and food are also known to cause Stevens-Johnson synd...