Congenital cystic adenomatoid malformation(CCAM): Symptoms,Diagnosis & Treatments
Congenital cystic adenomatoid malformation (CCAM) is the most common congenital lung disease and occurs sporadically regardless of race, age, and other factors. There are no known genetic polymorphisms and are known to cause 1-4 out of 100,000 people. It is a hamartomatous lesion composed of cystic and adenomatous tissue. Unlike pulmonary sequestration, blood is supplied through the pulmonary circulation and mainly affects one lobe of the lung. Because it is abnormally proliferating, not only the lung at the affected site but also the lung at the opposite site is also depressed, making it difficult to function. Diagnosis Among 5 types, the most common type is type 1 (60-70%). Type 1 CCAM exists as a 2 to 10 cm thin walled sac, not multiple. In addition, Type 2 CCAM is associated with congenital diseases of various organs such as esophageal atresia, tracheoesophageal fistula, and renal agenesis, and Type 4 CCAM is capable of malignant transformation. About 75% of children with pree...