Acute myeloblastic leukemia(AML): Treatments
If AML is diagnosed, the following treatments should be given to the patient. Long-term use of anthracycline and cytarabine, such as daunorubicin and idarubicin, has been suggested as induction chemotherapy, and etoposide or 6-thioguanide may be used recently. However, its advantages are unclear. Studies have shown complete remission (CR) in more than 70% of all AML patients when the following treatments were administered: To maintain this condition, consolidation is required, which involves the use of two courses of high dose cytarabine (HiDAC), or allogenic hematopoietic cell transplantation (HCT) to patients with high risk cyhtogenetics on the first CR. It is recommended that HCT be used as a consolidation treatment even in patients who have received chemotherapy such as cyclophosphamide or etoposide or who have undergone radiotherapy. In fact, it is known that HCT significantly reduces the risk of recurrence of AML, but there is a question about whether it increases survival rate b...