MedClips

Let's look at the Eisenmenger SD in chronological order. In the early phase, pulmonary arterial pressure rises with a noticeable increase in pulmonary blood flow. If this condition persists, it develops into a pulmonary vascular disease with pathological changes. This results in pulmonary hypertension. Pathological changes occur in small pulmonary arterioles and muscular arteries, and are divided into Grade I-VI according to histologic findings. In the early stage, medial hypertrophy occurs in Grade I, hyperplasia of intima in II, and obliteration in III. In IV, arterial dilation, V and VI eventually result in plexiform lesion, angiomatoid formation and fibrinoid necrosis. However, in the clinical setting, pulmonary artery resistance, pulmonary artery resistance, and systemic vascular resistance are observed rather than clinical course according to these histological changes. The retrospective study showed that the symptoms, syncope, poor functional class, low oxygen saturation (...